Posted in Clinical

Download Peptides and Non Peptides of Oncologic and Neuroendocrine by A. V. Schally (auth.), Eugenio E. Müller (eds.) PDF

By A. V. Schally (auth.), Eugenio E. Müller (eds.)

The booklet describes the facility of a chain of endocrine-derived compounds, i.e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert an instantaneous anti-neoplastic job or to potentiate the task of conventional chemotherapeutic brokers on neuroendocrine and reliable tumors. moreover, a brand new category of powerful GH-releasers, GSHs/Ghrelin, endowed with vital endocrine and extra-endcocrine motion, is gifted. consequently, as well as conventional chemotherapy, characterised by way of excessive toxicity and non-selective motion on tumoral cells, the reader can discover a new method with extra selective, much less cytotoxic endocrine derived compounds

Show description

Read or Download Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance: From Basic to Clinical Research PDF

Best clinical books

The Pathogenesis of Hypertensive Encephalopathy: Experimental Data and Their Clinical Relevance With Special Reference to Neurosurgical Patients

This monograph goals to supply a survey of modern learn at the pathogenesis of hypertensive encephalopathy. Or, in different phrases, to narrate experimental effects on to a medical challenge. i'm confident extremely important job of experimental clinical study is to discover functions to the proper scientific challenge once attainable, and to prevent distraction through an more and more over­ whelming accumulation of latest info from all fields of medical paintings.

Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance: From Basic to Clinical Research

The booklet describes the facility of a sequence of endocrine-derived compounds, i. e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert a right away anti-neoplastic job or to potentiate the job of conventional chemotherapeutic brokers on neuroendocrine and strong tumors. moreover, a brand new classification of powerful GH-releasers, GSHs/Ghrelin, endowed with very important endocrine and extra-endcocrine motion, is gifted.

Lifelines: Clinical Perspectives on Suicide

Suicide is a resource of never-ending disquiet. one of many few deadly effects of psychiatric sickness, it's a danger to sufferers, and a vexation to therapists that places medical judgment to the final word try. It arouses countertransference reactions of bizarre intensity-helplessness and guilt while the suicide is winning; nervousness and anger whilst it really is used as a manipulative device.

Interleukin-27: Biological Properties and Clinical Application

This quantity makes a speciality of a number of points of interleukin-27 (IL-27), particularly its strength for medical purposes. The authors talk about the downstream signaling from the IL-27 receptor and its molecular ambitions in immune cells together with Th1, Th2, Th17, Treg, Tr1, Tfh, B cells, DCs and macrophages. The inhibition of Th17 cells through IL-27 is essential for the upkeep of the feto-maternal tolerance and the prevention of lupus, a number of sclerosis, autoimmune uveitis, immune thrombocytopenia and atherosclerosis.

Extra resources for Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance: From Basic to Clinical Research

Sample text

Clinical trials with cetrorelix in patients with advanced renal cell carcinoma are in progress in New Orleans. , Hayakawa M. and Nakamura H. (1996). Gene expression of TGF-a, EGF and IL-6 in cultured renal tubular cells and renal cell carcinoma. Int J Urol, 3, 392-396. Barry M. and Roehrborn C. (1997). Management of benign prostatic hyperplasia. Annu Rev Med, 48, 177-189. , Shapiro E. K. (1995). Regional concentration of basic fibroblast growth factor in normal and benign hyperplastic human prostates.

Prostate, 44, 172-180. W. V. (1981). Inhibition of prostate tumor growth in two rat models by chronic administration of D-Trp6-LHRH. e. and Kvols 1. (1992). Somatostatin receptors in human renal cell carcinomas. Cancer Res, 52, 6074-6078. , Harvey H. and Redmond e. (1990). Endocrine treatment of breast cancer in women. Endocr Rev, 11, 221-265. V. (1988). Oncological applications of somatostatin analogs. Cancer Res, 48, 6977- 6985. V. (1999). Luteinizing hormone-releasing hormone analogs: their impact on the control of tumorigenesis.

3% vs. , 2000). 1 vs. , 2001). Larger randomized trials are needed to clarify the situation. LHRH Antagonists for Treatment of Uterine Fibroids Uterine fibroids represent the most common solid pelvic tumors and are associated with abnormal uterine bleeding and infertility. , 1985). Myomas are estrogen-dependent and rarely arise before puberty. Their progression stops after menopause. , 1995). , 1987), these compounds are mostly used to faciliate surgery by shrinkage of the fibroids if a uterus-conserving operation or vaginal hysterectomy is desired.

Download PDF sample

Rated 4.99 of 5 – based on 16 votes