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Download Clinical Aspects of Interferons by Frederick G. Hayden M.D. (auth.), Professor Michel Revel PDF

By Frederick G. Hayden M.D. (auth.), Professor Michel Revel (eds.)

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Eval. Pts. gator (Reference) N I,C 30 b. Site of lesion. treatment In one protocol, it study was (68), and using the observed that the same prominent success with the genital forms of HPV infection stands in sharp contrast to the complete lack of non-genital forms. (mucusa vs response in the This may be related to tissue factors multilayered skin, respectively), or to different sensitivity of various HPV subtypes to the IFN type and the treatment protocol used in that study. within the group of condylomata acuminata Even patients differences in results between some of the studies which employed similar IFN preparations and treatment schedule (60,61) may be However, in attributed another to study different such virus differences subtypes.

Eval. Pts. gator (Reference) N I,C 30 b. Site of lesion. treatment In one protocol, it study was (68), and using the observed that the same prominent success with the genital forms of HPV infection stands in sharp contrast to the complete lack of non-genital forms. (mucusa vs response in the This may be related to tissue factors multilayered skin, respectively), or to different sensitivity of various HPV subtypes to the IFN type and the treatment protocol used in that study. within the group of condylomata acuminata Even patients differences in results between some of the studies which employed similar IFN preparations and treatment schedule (60,61) may be However, in attributed another to study different such virus differences subtypes.

IFNB and IFN6), combination with other immuno- modulatory agents (50), thymic factors (51-53) and specific antibodies (54) or with chemical antiviral agents (55-56). 27 INTERFERON IN THE TREATMENT OF CONDYLOMATA ACUMINATA In contrast to HSV, papilloma viruses cannot be grown in vitro thus precluding the possibility to assess IFN effect on HPV replication in culture. On the other hand much more clinical data were accumulated in regard to HPV infections, particularly the genital results ones, were than HSV presented it investigators, is in Since infections.

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