Posted in Clinical

Download A Computational Model of Reasoning from the Clinical by Glenn D. Rennels M.D., Ph.D. (auth.) PDF

By Glenn D. Rennels M.D., Ph.D. (auth.)

As learn on specialist platforms has moved good into its moment decade, it has turn into renowned to quote the restrictions of the phenomenologic or associational method of wisdom illustration that used to be common of first iteration structures. for instance, the Internist-1 wisdom base represents explicitly over six hundred illnesses, encoding linked disorder manifestations (signs, indicators, actual findings, and lab abnormalities) yet failing to accommodate the explanations that these findings can be found in the illness [Miller, R. A. 82]. lately Pople has sought so as to add particular causal types to the information base in a revised model of this system referred to as CADUCEUS [Pople 82]. equally, a customary construction rule within the MYCIN approach states inferences which may be drawn while particular stipulations are chanced on to be real [Buchanan 84], however the underlying reasons for such relationships aren't encoded. Clancey has argued that MYCIN wishes such "supporting wisdom" represented, particularly if its wisdom base is for use for instructing reasons [Clancey 83]. through the overdue Seventies, synthetic intelligence researchers have been commencing to scan with reasoning platforms that used distinct mechanistic or causal niodels of the thing being analyzed. among the finest early examples have been a application to coach scholars the way to learn digital circuits [Brown eighty two] and a process for diagnosing issues of mechanical units [Rieger 76].

Show description

Read or Download A Computational Model of Reasoning from the Clinical Literature PDF

Similar clinical books

The Pathogenesis of Hypertensive Encephalopathy: Experimental Data and Their Clinical Relevance With Special Reference to Neurosurgical Patients

This monograph goals to supply a survey of contemporary study at the pathogenesis of hypertensive encephalopathy. Or, in different phrases, to narrate experimental effects on to a medical challenge. i'm confident extremely important activity of experimental clinical examine is to discover purposes to the correct scientific challenge once attainable, and to prevent distraction via an more and more over­ whelming accumulation of recent details from all fields of clinical paintings.

Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance: From Basic to Clinical Research

The publication describes the power of a chain of endocrine-derived compounds, i. e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert an immediate anti-neoplastic task or to potentiate the task of conventional chemotherapeutic brokers on neuroendocrine and stable tumors. additionally, a brand new category of powerful GH-releasers, GSHs/Ghrelin, endowed with very important endocrine and extra-endcocrine motion, is gifted.

Lifelines: Clinical Perspectives on Suicide

Suicide is a resource of unending disquiet. one of many few deadly results of psychiatric ailment, it's a possibility to sufferers, and a vexation to therapists that places scientific judgment to the last word try out. It arouses countertransference reactions of bizarre intensity-helplessness and guilt while the suicide is winning; nervousness and anger whilst it truly is used as a manipulative instrument.

Interleukin-27: Biological Properties and Clinical Application

This quantity specializes in a number of points of interleukin-27 (IL-27), particularly its power for medical functions. The authors talk about the downstream signaling from the IL-27 receptor and its molecular ambitions in immune cells together with Th1, Th2, Th17, Treg, Tr1, Tfh, B cells, DCs and macrophages. The inhibition of Th17 cells via IL-27 is key for the upkeep of the feto-maternal tolerance and the prevention of lupus, a number of sclerosis, autoimmune uveitis, immune thrombocytopenia and atherosclerosis.

Extra resources for A Computational Model of Reasoning from the Clinical Literature

Sample text

For example, there have been investigations into the use of specialty databases to yield prognostic information based on subsetting of the data [Rosati 75, deDombal 86]. This is in the same spirit as Roundsman because the researchers are looking for insight into individual patient prognoses. Precisely because of the interpretation difficulties mentioned above, investigators have studied database designs which lend themselves to statistical research such as the explicit introduction of time [Weyl 75].

Minimize the trauma of the procedure: hospital recovery time, repeated radiotherapy (RTX) visits, surgical morbidity, etc. 4. minimize the chance of tumor recurrence in the breast or chest wall even if the chance of overall survival is otherwise equivalent. ) 5. provide prognostic information for chemotherapy: on the basis of certain clinical studies, it is now believed that women with 1-3 histologically positive axillary nodes may benefit from chemotherapy. It is often the case, however, that no one treatment choice is optimal for all objectives.

This organizational view influenced the subsequent design of the Roundsman system. For example, in certain ways Roundsman's internal structures resemble a bibliographic retrieval system more than they resemble a traditional expert system. Overview of the Research and the Roundsman System 39 That is, knowledge resides in separately identifiable "articles" rather than being merged into a knowledge base of clinical rules. There are large differences between Roundsman and bibliographic retrieval systems, but they do have in common the organization of knowledge around separate publications.

Download PDF sample

Rated 4.77 of 5 – based on 49 votes